Metabolism Syndrome

Word-keys: Syndrome of Down, Obesidade, Metabolism. 1 INTRODUCTION Only in 1959, with the discovery and perfectioning of microscopy, was demonstrated that the individuals with Syndrome of Down (SD) were trissmicos for one of its chromosomes, originally identified as 21. The determinative ones of fentipo Down had been located in the trissomia of a segment of the long arm of chromosome 21. The incidence of the S.D sufficiently is correlated to the age materna. Women with more than 35 years of age give light more than 80% of the children with S.D. Studies tell the incidence of the S.D are three times bigger in children of women who had had infectious hepatitis before the gestation the increased occurrence of S.D in the advanced age materna are exponential, in any event, even so the causes are not total clear, the effect of the age sufficiently are established. The hypothesis of the fetal origin or programming has as basic principle to the nutricionais lacks suffered during stages from the fetal development and infancy, followed of better feeding in posterior stages of the life, being able to take to the sprouting of chronic-degenerative illnesses and obesidade.

One of the bases of this theory would be the occurrence of the low weight to the rising as resultant of the development of not transmissible illnesses chronic in the adult life. It is known that children with Syndrome of Down frequently are born with low weight, what could be one of the causes of the overweight/obesidade in the adult life. The interest in centering the study in the subject the occurrence of the obesidade in the carriers of Syndrome of Down appeared with the objective to study if a relation between the obesidade and the S.D exists. In this way we will search to focus the reason carrying people of S.D present a bigger probability to the development of the obesidade. .