When melanossomo is full of melanina, starts to receive the name from melanina granule. This last migra for the prolongations of the melancitos and is deposited in the cytoplasm of the queratincitos, that in turn, serve as melanina deposit. The melanina granules will go to merge themselves with the lisossomos of the queratincitos, being thus, the cells most superficial of the epidermis do not possess melanina. In the epithelial cells the melanina granules are in supernuclear localization, protecting, in this way the DNA against the actual damages for the solar rays. Other illnesses that affect the defense system generating illnesses, as melasma or cloasma, melanociticos hipercromias, nerves and melanoma. Causes or Etiology vitiligo still is an illness of unknown cause therefore no matter how hard the inquiries advance did not obtain to know the reason therefore the main one that it would join everything in a coherent explanation where incases the different factors is unknown.
Not if it can affirm until today that it has origin in the genetic predisposition, a time that this is only observed in only 30% of the cases in the same family but still thus the hypothesis was not discarded. They exist, however, some etiolgicas hypotheses that see vitiligo as a reply autoimune or associated the neurognicos factors, as well as the appearance of what it can be interposed by a variety of precipitantes causes Acreditava that vitiligo appears for the first time during a traumatic event, as an accident, loss of job, the death of a member of the family, serious solar burnings, or still a terrible illness. When the cause affects the imunolgico system, taking the body to react and starts eliminating pigment of the skin. The trauma leads in an area of the skin seems to around cause new spots – for example of the ankle due to friction with the footwear.